When biotech pioneer Dr. Wayne Ryan was forced out of the multimillion-dollar company he founded and led for decades, there was bound to be a legal dispute.His daughter was the CEO, while another daughter was the trustee of his estate, adding some significant family drama. But a Nebraska judge’s determination this summer that the founder’s shares of the company should be valued at $467 million, and his prejudgment interest should be $258 million, also made it something else: historic. The $725 million judgment is not …